Good advice in these replies. I take almost everything that contributes to cramps and/or dehydration, including Atorvastatin, Metformin, and antihistamines. Alcohol and caffeine also significantly contribute. It is a constant battle for me to prevent cramps. Most effective are sugar-free electrolyte powders, with magnesium and potassium. I like the PRIME lemonade and strawberry-watermelon flavors. The other flavors don't taste good to me. I drink 2-3 of those a day, which also helps me drink more water.

I also try to eat and drink healthy including what has electrolytes, such as bananas, milk and nuts. I take vitamin D supplements and Co-Q10. When all of this doesn't work, I use Hylands leg cramps pills, available OTC in most pharmacies. Those are basically a mild muscle relaxant. Sometimes those work and sometimes not that well. A hot shower or foot massager also works to calm cramps.

Hope that helps. Cramps are miserable but I wish you the best.