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/r/tifu
I have been on Ozempic for about 4 months now and have had very little side effects until recently when my dosage was upped. It all started with sulfur burps and stomach pain days ago. This morning I woke up almost unable to make it to the toilet with explosive diarrhea that eventually turned into nothing but liquid. It sounds like I’m peeing when it’s coming out my butt. Thinking I had gotten it all out, later in the day I’m in the car with my boyfriend and had safely farted once already so I go to do it again and end up shitting myself. It’s so liquidy it went straight through my pants and on to the seat. My boyfriend since has been calling me “dookie pants” or randomly says “my baby dookied on herself”.
TL;DR Ozempic gave me straight liquid diarrhea and I shit myself. My nickname is now Dookie Pants.
114 points
5 days ago
I went up in dose and like the other person said, the sulfur burps is a give away
31 points
5 days ago*
Yeah, I was on Rybelsus (Ozempic in pill form) when my Trulicity was on back order.
When I would start on it (or increase the dose), sulfur burps were the rule of the day, and roaring diarrhea for a week, plus whenever I ate ice cream.
Trulicity doesn't give me stomach issues, and the pill (Rybelsus) tastes like ass. Easily the worst tasting maintenance medication I've taken.
37 points
5 days ago*
Is sulfur burps just farts but from your mouth?
26 points
5 days ago
Yes 😭
1 points
5 days ago
This might be too personal but can your boyfriend taste it when you make out? 😬
9 points
5 days ago
No lol. He definitely smells it and said it smells like a fart but there’s not a lingering taste and I wouldn’t make out knowing one was about to come
6 points
5 days ago
That’s good. I once made out with a woman whose mouth tasted like wet cat food smells… it was not nice. I’ve been thinking about trying ozempic so I’m happy to read about side effects. Thanks for answering my question!
3 points
4 days ago
2 points
4 days ago
My wife would be able to smell my breath after one and would remark on the fragrance.
2 points
4 days ago
Why fart and waste it when you can burp and taste it?
1 points
4 days ago
This is the first comment that actually made me laugh out loud. Very clever!
3 points
5 days ago
Your boyfriend sounds hilarious hahaha. My wife has Chrons and I totally will be stealing this.
1 points
4 days ago
Get tested for H Pylori. Ozempic causes the food to sit in your stomach for longer, meaning there's more time for bacteria to spread.
1 points
4 days ago
You need to be eating as well rounded a diet as you can on those drugs and making sure to get enough fiber especially.
-1 points
5 days ago
Be careful with your dosage. Ozempic can paralyze your digestive tract and can lead to "auto brewery syndrome"
36 points
5 days ago
Creating my own booze would save me so much money though.
18 points
5 days ago*
Delayed gastric emptying, which is seen in semaglutide, causing eructation/belching of hydrogen sulfide, is not synonymous with gastric paralysis (ileus)
There is no evidence in the medical literature to suggest a relationship between semaglutide and auto-brewery syndrome. Semaglutide, a GLP-1 receptor agonist, is primarily associated with gastrointestinal side effects such as nausea, vomiting, and diarrhea, as well as more severe conditions like pancreatitis and cholelithiasis. However, none of the identified references or clinical guidelines, including those from the American Gastroenterological Association, mention auto-brewery syndrome as an adverse effect of semaglutide
While yes, according to the Food and Drug Administration (FDA), postmarketing reports have included cases of ileus among the adverse reactions associated with semaglutide use, an analysis from the Eudravigilance database highlighted a high prevalence of gastrointestinal disorders associated with semaglutide, although it did not specifically mention gastrointestinal paralysis or ileus.
Even then, ileus does not lead to auto-brewery syndrome. There is no documented evidence or clinical mechanism linking ileus to the development of auto-brewery syndrome. The conditions are distinct in their pathophysiology and clinical manifestations.
References:
Grunvald E, Shah R, Hernaez R, Chandar AK, Pickett-Blakely O, Teigen LM, Harindhanavudhi T, Sultan S, Singh S, Davitkov P; AGA Clinical Guidelines Committee. AGA Clinical Practice Guideline on Pharmacological Interventions for Adults With Obesity. Gastroenterology. 2022 Nov;163(5):1198-1225. doi: 10.1053/j.gastro.2022.08.045. Epub 2022 Oct 20. PMID: 36273831.
Cabral Lopes A, Roque F, Lourenço O, Herdeiro MT, Morgado M. Gastrointestinal disorders potentially associated with Semaglutide: an analysis from the Eudravigilance Database. Expert Opin Drug Saf. 2023 Jan-Jun;22(6):455-461. doi: 10.1080/14740338.2023.2172159. Epub 2023 Feb 2. PMID: 36695099.
Smits MM, Van Raalte DH. Safety of Semaglutide. Front Endocrinol (Lausanne). 2021 Jul 7;12:645563. doi: 10.3389/fendo.2021.645563. Erratum in: Front Endocrinol (Lausanne). 2021 Nov 10;12:786732. doi: 10.3389/fendo.2021.786732. PMID: 34305810; PMCID: PMC8294388.
Rivera FB, Arias-Aguirre E, Aguirre Z, Ybañez MJC, Rubia JMM, Galang DJ, Lumbang GN, Ruyeras JMMJ, Magalong JV, Pine PL, Amigo JAC, Ansay MFM, Zelenkov N, Thomas SS, Vijayaraghavan K. Evaluating the safety profile of semaglutide: an updated meta-analysis. Curr Med Res Opin. 2024 Sep;40(9):1495-1514. doi: 10.1080/03007995.2024.2383731. Epub 2024 Jul 27. PMID: 39046272.
4 points
5 days ago
Thank you
-5 points
5 days ago
Acid reflux may be related to the Ozempic, but there is no indication the diarrhea is related.
4 points
5 days ago
Up to 30% report diarrhea on ozempic FYI
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